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Research & Publications

Dr Roy Chowdhury is the clinical trial administrator of Saroj Gupta Cancer Centre and Research Institute, Thakurpukur, Kolkata. Here he plays a pivotal role in driving both clinical and academic research trials in the institute.
He is a keen researcher and collaborates on various projects with scientists from National Institute of Bio Medical Genomics (NIBMG), Kalyani, Indian Institute of Chemical Biology, Jadavpur, Kolkata and various departments of University of Calcutta.

At present he is involved in the following projects:

  • A prospective non-randomised trial of Squamous Cell Carcinoma of cervix uteri of stage IB2, IIA, IIB pretreated with three cycles of Neo Adjuvant Chemotherapy (NACT) followed by surgery after down-staging to stage IB1 followed by active surveillance. Dr N R Mondal, Dr R Roy Chowdhury, Dr Biman Chakrabarti, Dr T Chatterjee, Dr J Basak (Dept of Gynaecological Oncology SGCCRI)
  • Variation in human gene expression among women from four states of India: genomic correlates, gene regulation and impact on HPV16 related cervical cancer pathogenesis.              Dr Sharmila Sengupta, National Institute of Biomedical Genomics, Kalyani, Dr N R Mondal , Dr R Roy Chowdhury (Dept of Gynaeoncology), SGCCRI, Thakurpukur
  • Association of genetic polymorphism of matrix metalloproteinases (MMPs) and their expression in epithelial ovarian cancer. Dr Susri Ray Chaudhuri PhD (Research Associate), IICB, Dr Snehaswikta Swarnakar, Senior Scientist IICB, Dr Rahul Roy Chowdhury MRCOG, SGCCRI Thakurpukur [ ICMR funded project]
  • HPV 16 Methylome, methylation and gene expression status of host genes: influence on cervical cancer pathogenesis.- Dr Rahul Roy Chowdhury, SGCCRI and Dr Sharmila Sengupta NIBMG
  • A Phase II Clinical Study to evaluate the efficacy and safety of NRC – AN – 019 in cancer patients failing standard prior therapies – Dr Samir Bhattacharyya, SGCCRI, Dr R N Ghosh, Dr Arnab Gupta, Dr Saradindu Ghosh, Dr Rakesh Roy, Dr Rahul Roy Chowdhury.
  • HPV 16 Methylome, methylation and gene expression status of host genes: influence on cervical cancer pathogenesis.- Dr Rahul Roy Chowdhury, SGCCRI and Dr Sharmila Sengupta NIBMG

His recent publications include:

  • S Ray Chaudhuri Guha, A Roy, I Chatterjee, R Roy Chowdhury, S Swarnakar. Landscape of Papillomavirus in human cancers: Prevention and therapeutic avenues. Book Chapter in Cancer-causing viruses and their inhibitors. S P Gupta and V Gautam Eds. CRC press; May 2014; 207- 242.
  • Mandal P, Bhattacharjee B, Das Ghosh D, Mondal NR, Roy Chowdhury R, et al. (2013) Differential Expression of HPV16 L2 Gene in Cervical Cancers Harboring Episomal HPV16 Genomes: Influence of Synonymous and Non-Coding Region Variations. PLoS ONE 8(6): e65647. doi:10.1371/journal.pone.0065647
  • Das Ghosh D, Bhattacharjee B, Sen S, Premi L, Mukhopadhyay I, Roy Chowdhury R, Roy S, Sengupta S. (2012) Some Novel Insights on HPV16 Related Cervical Cancer Pathogenesis Based on Analyses of LCR Methylation, Viral Load, E7 and E2/E4 Expressions. PLoS ONE 7(9): e44678. doi:10.1371/journal.pone.0044678
  • *Ray Chaudhuri (Guha) S, *Banerjee P, *Yadav DK, **Roy Chowdhury R, **Mondal NR, *Swarnakar S. Search for an alternative bio-marker for prognosis of Epithelial Ovarian Cancer – Poster presentation  (SPP 42) at the 1st International Meet on Cell Signaling Network (CeSiN 2012); 11 – 13
  • Epidemiology of Vulval Malignancy.
  • Chakrabarti Biman Kumar, Roy Chowdhury Rahul, Chatterjee Tanmoy, Mondal Nidhu Ranjan.
    Poster presented in the XX FIGO World Congress of Gynecology and Obstetrics. Rome 7 – 12  October 2012. ABT11 – Gyne-oncology DOI: 10.3252/
  • Guha S, Roy Chowdhury R (2007). A long-term study of women with normal colposcopy after referral with low-grade cytological abnormalities. BJOG: An International Journal of Obstetrics and Gynaecology 114 (4), 508–508. (doi:10.1111/j.1471-0528.2006.01253.x)
  • Bridging Links Between Long Noncoding RNA HOTAIR and HPV oncoprotein E7 in cervical Cancer Pathogenesis. Sweta Samanta, Paramita Mmandal, Rahul Roy chowdhury, Tamal Sadhukhan, Nidhu ranjan Mandal, Biman Chakravarty. Scientific Reports (Impact Factor: 5.58). 07/2015; 5:11724. DOI: 10.1038/srep11724 Source: PubMed

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